The History of Mesotherapy
Mesotherapy is a technique, invented in 1952 by Dr. Michel Pistor, where medication is injected into the mesoderm, the layer of fat and connective tissue under the skin. Over the past 50+ years, in excess of 50,000 physicians worldwide have used Mesotherapy regularly for a variety of purposes, including overall weight loss, spot weight reduction, cellulite reduction, hair loss, scar revision and wrinkle elimination.

In 1987, the French Academy of Medicine recognized Mesotherapy as an inherent part of traditional medicine. The International Society of Mesotherapy encompasses 14 countries throughout Europe and South America.

Mesotherapy is a technique using very small doses of compounded medications that are administered in specific areas, depending on the condition being treated. The medicines and plant extracts used are typically obtained from compounding pharmacies in most countries, although Europe mass manufactures many products that are prohibited for import into most other countries. 

All medicines used are FDA-approved for their use. In combination, medicines for Mesotherapy are used for off-label purposes. A recent illustration of this distinction is Botox. Although Botox was FDA approved for controlling muscle spasms, the medical community embraced it for its cosmetic properties of controlling wrinkles. For many years, plastic surgeons and dermatologists used Botox for off-label purposes.

Uses for Mesotherapy
Dr. Jacque Le Coz, former president of the French Society of Mesotherapy and Mesotherapist for the French National Sports Teams, has written three books on Mesotherapy, including Mesotherapie et medecine esthetique (Solal Publishing, France), Mesotherapie et traumatologie sportive (Masson Publishing, France), and Mesotherapie en medecine generale. Dr. Le Coz outlines more than 120 conditions that Mesotherapy has shown to be effective for including the following:

  • Cellulite Face & Neck Rejuvenation
  • Scars
  • Hyperpigmentation
  • Fat Reduction
  • Flaccid Skin
  • Stretch Marks
  • Migrane Headaches
  • Wrinkles
  • Tendonitis
  • Scars
  • Alopecia
  • Arthritis
  • Sports Trauma
  • Hyperkeratosis
  • Acne
  • Bone Spurs....

Mesotherapy & Aesthetic Medicine
Mesotherapy strengthens elastin fibres, stimulates collagen production, fights free radicals and stimulates cellular activity. Patients report Your can expect good results in your patients - loose skin to appear firmer and look younger and healthier, fine lines will be reduced and skin will “glow” as a result of Mesotherapy Treatments.  

Many Mesotherapists practice the specialty of Medical Aesthetics because of the beautifying effects it has on the skin. Wrinkles, cellulite and skin rejuvenation are the most effective complaints successfully treated with Mesotherapy. Mesotherapy in combination with Botox for whole face treatments are also revealing overwhelming results.

The primary reason these injections are so effective for wrinkles and cellulite is that when administered correctly the injections reach not only the different layers of the skin, but the subcutaneous fat as well, helping reverse the physiology.  

Cellulite is a condition in which abnormal "nodules" of fat form in the midsection and thighs, more commonly in women than men. This gives the appearance of a ruffling of the skin. The condition is caused by abnormal physiology in the skin and subcutaneous fat. It involves a type of insufficiency in the venolymphatic system. Mesotherapy injections are given to not only improve the venous and lymphatic flow, but to also break down the fat nodules. The solutions generally consist of a vasodilator, lymph flow stimulator, and an anesthetic.

Because cellulite involves an abnormality in fat accumulation, Mesotherapy injections should be done in conjunction with a comprehensive natural medicine program designed to improve overall metabolism. This would have the effect of increasing weight loss and improving overall health. Hormone imbalances are often at the core of the problem and need to be corrected to have maximum benefits. If the underlying physiology is corrected and maintained, then Mesotherapy is done in an initial series. If it recurs, then the process will need to be repeated.

Wrinkles, like other conditions involving the skin, have a multi-factorial etiology.

Excessive skin wrinkles can be caused by: overall dehydration, excessive sun exposure, genetics, facial expressions, muscle atrophy, fatty acid deficiencies, hormone imbalances, nutrient deficiencies, and many other causes.

As with cellulite treatment, it is best to utilise Mesotherapy for wrinkles in the context of a comprehensive natural medicine program to correct some of the above causes.

For the person with stress and increased muscle contraction in the forehead, Botox injections can be given along side the Mesotherapy treatment.

MesoBotox is a the term which involves injecting multiple small doses of BOTOX into the skin of the face to reduce the action of sweat and sebaceous glands as well as the superficial layer of facial muscles which are responsible for those very fine, annoying lines of the forehead or under the eyes. The net effect is improved sheen of the face with smooth skin, tighter pores and yet the ability to move all the deeper muscles of the face thus retaining a natural, non “plastic” appearance. Patient feedback has found that MesoBotox is a welcome complement to traditional BOTOX injections.

Excessive wrinkles can also be a sign of advanced or aggressive aging, which emphasizes the need even more to utilize Mesotherapy, along side of a comprehensive Mid-Life Medicine regime. This may involve the use of regenerative therapies, natural hormone replacement, nutraceuticals, appropriate metabolic-type diet, and other Mid-Life Medicine measures.

As with cellulite, Mesotherapy for wrinkles may often need to be repeated after the initial series.

Skin Rejuvenation - Mesolift
The aging process can be cruel to our skin - Between sun damage and progressive collagen loss, the skin loses its plumpness and resiliency.

Mesotherapy skin rejuvenation or “Mesolift” infuses the dermis with potent vitamins and anti-oxidants to rejuvenate and revitalize the skin.

People who have had a “Mesolift” describe their skin as firm, radiant, youthful and glowing.

The "Mesolift" is usually performed in an initial series of 2-4 treatments spaced a week apart. Results are maintained by twice a year touch up sessions.

Lipolysis - MesoSculpting - “The New Liposuction” 
Is it possible to get rid of fat without having some kind of invasive procedure?...This
has long been a question pondered by many.

The Mesotherapy
Treatment procedure that uses Phophatydlcholine, also known as "MesoSculpting" or "Lipodissolve" is proving to answer the question with a resounding "yes".

MesoSculpting for fat loss and body contouring is great news for patients who find the idea of liposuction “too much”. It is also the answer to those patients who have already had liposuction and have been left with the fat deposits around the area they had the liposuction surgery done. These fat deposits post liposuction surgery is quite common.

MesoSculpting involves microinjections using various formulas. All formulas must contain Phosphatydlcholine to achieve the lipolytic effect. The injections are given directly into the areas being treated i.e. love handles, bra bulge, saddlebags, inner thighs, arms, knees, eye fat pads, double chin etc. 

Results are considered permanent as long as the patient adheres to a proper nutrition and exercise regimen.

Occasional touch-ups may be required.

Mesotherapy for Cellulite
The main concern for many women around the globe is cellulite. The ugly, dimply, orange-skin appearance that is obvious even on the thinnest of thighs. That’s not surprising when you consider cellulite is a skin condition affecting over 90% of most post-pubescent women.

Cellulite is not caused by being overweight at all and can affect even slim figured women in all areas of the body – thighs, hips, buttocks, stomach, knees and even upper arms... Patients often complain about the external visible appearance of cellulite — lumpy, dimpled appearance. Cellulite commonly appears on the hips, buttocks and legs, but is not caused by being overweight, as many believe.

Cellulite appears in the subcutaneous level of skin tissue. Fat cells are arranged in chambers surrounded by connective tissue called septae. As water is retained, fat cells held within the perimeters of this area expand and stretch the connective tissue. Eventually this connective tissue contracts and hardens (sclerosis) holding the skin at a non-flexible length, while the surrounding tissue continues to expand with weight, or water gain. This then results in areas of the skin being held down while other sections bulge outward, resulting in the dimply 'cottage-cheese' appearance.

Studies have
Shown Mesotherapy to effectively reduce cellulite. This is due to the following facts:

1. Improves blood flow to the area...
2. Dissolves excess fat deposits...
3. Removes fibrotic, hardened connective tissue...
4. Improves lymphatic drainage...


Meostherapy Technique

Localized Fat



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Disclaimer and terms of issue: The information in this website has been compiled with all care, however the reader accepts the authors intention is not to provide any medical advice of any kind .The onus & responsibility of the application of any of the suggestions made in this website lies with the reader in consultation with a qualified medical practitioner. The practice of Mesotherapy or any medical application should be done under the strict supervision of a registered & qualified medical practitioner. Patients should be thoroughly examined prior to any treatment & closely monitored after it's commencement.